PROTAC — Targeted protein degradation strategy

2026年01月07日 15:07

PROTAC technology advances targeted protein degradation by enabling catalytic removal of disease-relevant proteins through E3 ligase recruitment. The documents emphasize rational degrader design and optimization, along with quantitative strategies to assess degradation potency, selectivity, and downstream functional consequences across in vitro and in vivo settings. The white paper covers principles and evaluation logic, while the technical guide provides assay workflows and interpretation.

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PROTAC ---- implementation guide

2026-01-07 15:07:33.531

21.7MB

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Chemical Proteomics
Spatial Proteomics
Targeted Degradation
Self-Assembly Systems
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