Chemical proteomics — Target engagement & MoA elucidation
2026年01月07日 15:08
Chemical proteomics enables proteome-wide interrogation of small-molecule engagement in biologically relevant systems. By combining probe-based enrichment and mass spectrometry with orthogonal validation, it supports robust target identification, mechanism-of-action elucidation, and off-target risk assessment to strengthen translational confidence. The white paper focuses on concepts and applications, while the implementation guide details workflows, controls, and QC.
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2026-01-07 15:08:03.056
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Chemical proteomics enables proteome-wide interrogation of small-molecule engagement in biologically relevant systems. By combining probe-based enrichment and mass spectrometry with orthogonal validation, it supports robust target identification, mechanism-of-action elucidation, and off-target risk assessment to strengthen translational confidence. The white paper focuses on concepts and applications, while the implementation guide details workflows, controls, and QC.